What is 2 to the power of 16 ?What is 2 to the power of 16 ?Solution: 216 = 65536simplify this: All that is needed is to multiply it out:2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2 x 2= 65536 So, 2 to the power of 16 is 65536.