What is 4 to the power of 16 ?What is 4 to the power of 16 ?Solution: 416 = 4294967296simplify this: All that is needed is to multiply it out:4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 x 4 = 4294967296 So, 4 to the power of 16 is 4294967296.